Energi
Lysglad gjær kan endre vår tilnærming til biodrivstoff
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Lys er liv
Nesten all energi i menneskelig sivilisasjon er i siste instans hentet fra solen. Mat, biomasse og tre vokser takket være sollys. Og kull, gass og olje er laget av døde planter fra millioner av år siden. Selv vindene er resultatet av at solen varmer opp atmosfæren. Og selvfølgelig har vi i dag solcellepaneler. Når man ser på hvor mye av vårt energibehov som de levende organismene dekker ved å utnytte solens kraft, gir konseptet biodrivstoff mening.
Problemet er at første- og andre-generasjons biodrivstoff, som bruker avlinger som mais og sukkerrør eller jordbruksrester, har en relativt dårlig energiytelse på grunn av hvor mye fossilt brensel og gjødsel som brukes til å dyrke disse avlingene.
Kilde: Unsplash
Biodrivstoff av tredje generasjon ser på å bruke alger i stedet, noe vi diskuterte i mer detalj i artikkelen vår «Algal biodrivstoff: Den neste energirevolusjonen?».
Men hva om vi kunne få alle organismer til å kunne utføre fotosyntese? Det som hittil har vært en fjern drøm, er delvis oppnådd av forskere ved Georgia Tech.
Lysdrevet gjær
Gjær er kanskje den best forståtte mikroorganismen i verden. Mennesker har utnyttet gjærs biokjemiske evner til å produsere brød, alkohol og fermenterte melkeprodukter siden sivilisasjonens begynnelse.
Gjær er også en av de mest vanlige organisme‑«modellene» i biologilaboratorier. Og viktige bio‑fabrikker for mange medisiner og nyttige biomolekyler.
Likevel må gjær mates med sukker eller andre forbindelser for å holde seg i live. I hvert fall var dette sant inntil Anthony Burnetti, en forskningsforsker som arbeider i professor William Ratcliffs laboratorium, klarte å få gjær til å kunne høste energien fra lys.
«Alt vi trengte å gjøre var å flytte ett enkelt gen, og de vokste 2 % raskere i lys enn i mørke. Uten noen finjustering eller nøye oppmuntring, så fungerte det bare.»
Fullstendig ny type gjær
Teamet har erfaring med å endre gjær, en vanlig og allestedsnærværende organisme med nytt og uventet potensial. Mest bemerkelsesverdig har de tidligere klart å omdanne den encellede gjæren til en kompleks flercellede organisme i «Multicellularity Long-Term Evolution Experiment».
Kilde: Georgia Tech
En begrensning for veksten av disse flercellede gjærorganismene var tilgangen til oksygen i de indre «vevet». Dette er grunnen til at de fortsatte med å gjøre gjær til en fotosyntetisk organisme.
For å gjøre dette, la de til et protein, rhodopsin, i gjæren. Dette proteinet er kjent for å utføre en viss fotosyntese uten de komplekse proteinene og biomolekylene som finnes i høyere planter (som klorofyll).
Bare ved å legge til ett gen som koder for et rhodopsin‑protein, kunne gjæren fange lys og vokse raskere. Økningen var beskjeden, kun +2 % vekstrate, men betydningsfull på grunn av den enkle endringen. Og denne økte veksten er ennå ikke optimalisert.
Biodrivstoff med syntetisk biologi
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