शोधकर्ता मानव दीर्घायु के रहस्यों को खोलने की कोशिश कर रहे हैं

Since the dawn of time, man has contemplated ways to live forever. While this goal remains science fiction, major healthcare and technology breakthroughs have resulted in extended human longevity. People live longer today than ever, and reports indicate that the trend will continue into the foreseeable future. Here’s everything you need to know about how new advancements extend human longevity.

आंकड़े झूठ नहीं बोलते

Several अध्ययन examining extending life expectancies have provided some interesting results. For example, a report from the Bill & Melinda Gates Foundation and coordinated by the Institute for Health Metrics and Evaluation (IHME) revealed that the average life expectancy of a female in the US will increase from 73.6 years in 2022 to 78.1 years by 2050. This report revealed a longer life expectancy of +0-27 years between 1990 and 2019 as well.

The data revealed that the biggest increase in life expectancy will come from the countries with the lowest longevity currently. These nations will quickly gain access to healthcare and other services that will make this transformation a possibility according to researchers. This discovery was in stark contrast to what many analysts believed the scenario would be, superpowers experiencing the largest life expectancy increases.

लोग अधिक समय तक कैसे जीवित रहेंगे?

There are some interesting ways in which your life expectancy may increase in the future. Researchers continue to delve into various methods and sciences to ward off the effects of old age and extend youth and health. Here are a few interesting studies that should help you understand that the race for human longevity has many paths.

मानव दीर्घायु को बढ़ावा देने वाले एंटी-एजिंग दवाएँ

The idea of an age-defying elixir has been a concept since ancient civilizations. There are moments in history when dignitaries and others attempted some crazy ways to stop the effects of time. For example, cinnabar (mercuric sulfide) was commonly used in makeup products in ancient cultures, resulting in disease and death.

सौभाग्य से, विज्ञान सच्चे एंटी-एजिंग सीरम को खोजने के करीब हो सकता है। जर्नल Fly में प्रकाशित एक अध्ययन ने जीवन प्रत्याशा बढ़ाने के लिए Mifepristone और Rapamycin के उपयोग की जांच की। शोधकर्ताओं ने फल मक्खियों को विषय के रूप में उपयोग किया, जिन्हें उन्होंने एक गैर-आक्रामक विधि से मॉनिटर किया।

स्रोत – Ourworldindata

इंजीनियरों ने देखा कि Mifepristone और Rapamycin दोनों ने मक्खी की जीवन प्रत्याशा को थोड़ा बढ़ाया, क्योंकि उन्होंने कोशिका की मिटोफैगी को रोकने की क्षमता को बढ़ाया, जिससे आपकी कोशिका के माइटोकॉन्ड्रिया का स्वास्थ्य पुनर्स्थापित हुआ। मनुष्य उम्र बढ़ने के साथ स्वाभाविक रूप से इस क्षमता को खो देते हैं।

अध्ययन के परिणामों से पता चला कि दोनों दवाओं ने इस क्षमता को थोड़ा सुधार दिया। हालांकि, जब इन्हें साथ में उपयोग किया गया, तो परिणाम में सुधार नहीं हुआ, जिससे शोधकर्ताओं ने निष्कर्ष निकाला कि वे समान रूप से कार्य करती हैं। उल्लेखनीय है कि परीक्षण USC Dornsife College of Letters, Arts, and Sciences में किया गया और National Institute on Aging के ग्रांट R01AG057741 द्वारा वित्तपोषित था।

Now engineers seek to get approval for further testing of the drugs on humans. Thankfully,  these drugs are both used for other purposes currently,  making it easier to get them approved as anti-aging drugs if the benefits are clinically proven.

कार्डियो फिटनेस मानव दीर्घायु को बढ़ाता है

It may not be a huge surprise to learn that there is a strong connection between your cardiovascular health and your life expectancy for most people. However, according to a new रिपोर्ट published in the British Journal of Sports Medicine (BJSM), this connection is far greater than once thought. A team of researchers examined +20.9 million observations from 199 unique research groups, seeking out the correlation.

The researchers discovered that the better your body is at supplying oxygen during intense activities, the longer you are likely to live. It also showed that you’re less likely to develop diseases when you consistently enhance your blood flow by working out and staying active. This data demonstrates how high levels of cardiorespiratory fitness may be one of the best ways to ward off diseases like type 2 diabetes, metabolic syndrome, cancers, stroke, and depression.

माइक्रोबायोम अनुकूलन मानव दीर्घायु को सुधार सकता है।

Another रिपोर्ट found that your gut microbiome is a crucial component that could dictate how long you live. Your microbiome is home to billions of microorganisms that all play a part in your health, digestion, and bodily functions. This critical component of your anatomy dictates your nutrition absorption, immune system health, hormone levels, metabolism, and much more.

Researchers have discovered that those with healthier gut microbiomes enjoy a reduced risk of various chronic diseases. As such, enhancing your microbiome can help you live longer and healthier. To improve your microbiome, you don’t need anything special. A healthy diet, which includes pro and prebiotics, can make a difference.

वॉटर-बेयर मुख्य कुंजी हो सकता है

Nature is full of creatures that seem to ward off aging or sickness through unimaginably harsh conditions. In the past, engineers have looked towards jellyfish, lobsters, tortoises, and other animals to reveal some of their longevity secrets. A recent study shrinks the subjects to a microscopic level in search of results.

टारडिग्रेड, या वॉटर बेयर, एक छोटा आर्थ्रोपॉड है जो कुछ पागलपन भरी परिस्थितियों में भी जीवित रह सकता है। उदाहरण के लिए, ये छोटे जीव वर्षों तक हाइबरनेट कर सकते हैं, पानी की प्रतीक्षा में। वे वैक्यूम में 8 दिन और ऑक्सीजन-रहित वातावरण में 3 दिन तक जीवित रह सकते हैं।

The researchers wanted to study the secret to their ability to slow down their cell metabolism, called biostasis. According to a recent रिपोर्ट, the CAHS protein was discovered to be a main component in the process, leading researchers to isolate and create engineered human cell CAHS proteins. These genetically engineered cells will undergo further testing to see how resilient they are compared to their water-bear cousins.

मानव दीर्घायु को बढ़ाने के अत्यधिक तरीके

Of course, no search for the fountain of youth would be complete without some highly controversial methods. From siphoning blood from younger generations to editing your genes, there are plenty of methods of extending your life that have raised eyebrows with concern.

युवा रक्त संक्रमण

The concept of a blood transfusion to improve health isn’t anything new. Healthcare professionals have conducted blood transfusion since its introduction in 1665. Of Course, back then, the process was only being tested on dogs. It wouldn’t be until the 1900s that the human blood groups would be discovered, paving the way for human transfusions.

पहले रक्त संक्रमण के बाद से, यह दावा किया गया है कि प्रक्रिया युवा रक्त प्रदान करके वृद्धों को पुनरुज्जीवित कर सकती है। हालांकि, हाल तक ये केवल अप्रमाणित दावे थे। एक नया अध्ययन युवा चूहे के रक्त को वृद्ध चूहे में संक्रमण करने की जांच करता है।

The researchers tracked the improvements in health. Surprisingly, there were substantial improvements in the older mice’s vigor, circulation, and overall health. Now, the team wants to conduct similar studies in human patients. However, it has received significant backlash for what many see as a potential vampire-like scenario where the wealthy would siphon the less fortunate youth like a sci-fi horror film.

अपने जीन संपादित करें

Gene splicing technology continues to improve, and systems like CRISPR-Cas9 have made the process far more stable and predictive. The concept of gene splicing to enhance longevity is simple. Find the genes that are aging and replace them. Now, researchers envision a day when they can alter your genetic code to prevent diseases and other genetic ailments.

This technology even enables future parents to make समायोजन to their children’s features and more. As you would imagine, this controversial approach to extending human life has seen some pushback from those who see the potential for abuse in the future. For now, CRISPR tech and other gene splicing options remain at the forefront of extending life expectancy research.

मानव दीर्घायु को बढ़ाने की दिशा में लाभ उठा सकने वाली कंपनियाँ

The market is full of companies that have a lot to gain from the research conducted in extending human life expectancy. From healthcare providers to those shipping medications, there is a massive economy relying on people’s desire to live longer. Here’s one firm positioned perfectly to see some upswing from this trend.

Generation Bio Inc.

Generation Bio Inc.   एक प्रमुख जीन थेरेपी दवा प्रदाता है। कंपनी कैम्ब्रिज में स्थित है और 2016 में मार्क डी. एंजेलिनो, जेसन पी. रोड्स और रॉबर्ट एम. कोटिन द्वारा स्थापित की गई थी। अपनी शुरुआत के बाद से, Generation Bio ने अगली पीढ़ी की जीन थेरेपी में अग्रणी भूमिका निभाई है, जिसमें cDNA और ctLNP का रिलीज़ शामिल है, जो नैनो पार्टिकल्स को डिलीवर करने के लिए डिज़ाइन किए गए हैं।

Generation Bio बाजार में मजबूत स्थिति रखती है और उल्लेखित विभिन्न तकनीकों को प्रस्तुत करने के लिए आदर्श रूप से उपयुक्त है। कंपनी का मार्केट कैप $156.84M है और इस वर्ष अब तक $5.9M का राजस्व दिखाया है। वर्तमान में यह +174 पेशेवरों को रोजगार देती है। दिलचस्प बात यह है कि GBIO ने कई अन्य स्वास्थ्य देखभाल स्टॉक्स के साथ कुछ कमियों को देखा है, लेकिन हाल ही में ऊपर की गति दिखाना शुरू किया है। कंपनी की स्थिति और अनूठी उत्पाद श्रृंखला को देखते हुए, GBIO एक समझदार स्टॉक है जिसे देखना चाहिए।

मानव दीर्घायु – अधिक समय जीवित रहना बेहतर नहीं है

Sadly a study conducted by the Global Burden of Disease Study (GBD) 2021 that showed the elderly will be around longer but they will suffer from a range of extended health complications during their longer life. Interestingly, these diseases will be largely non-communicable ailments, including chronic obstructive pulmonary disease, cancer, diabetes, and cardiovascular diseases.

मानव दीर्घायु – युवा के फव्वारे की खोज

There are many different ways in which researchers seek to enable you to live longer. These strategies are just a few of the thousands of different approaches that people have taken over the years. However, unlike your ancestors, these recent attempts enjoy the most advanced testing and simulation capabilities, making them by far the most effective to date. As such, you should start planning to live a bit longer than expected.

अन्य आकर्षक स्वास्थ्य तकनीक विकास के बारे में अब जानें।